Tanja Wenzel is perhaps best known to German TV viewers for her recurring role as Isabell Mohr / Brandner on the German Das Erste TV network soap opera series ''Verbotene Liebe'', which she appeared on from 1999-2004, and her recurring role as Melissa Brock on the drama series ''Alles oder Nichts'' in 2018-2019. Tanja also appeared in the movies ''Der Wixxer'' (2004), ''Wo ist Fred?'' (2006) and the comedy ''Vollidiot'' (2007).
In addition to her TV role on ''Verbotene Liebe'', Tanja also appeared in the recurring role of Annette Darcy on the German telenovela series ''Anna und die Leibe'' (2009-2010). Tanja is good friends with fellow German actress Katharina Dalichau, with whom she co-starred with on ''Verbotene Liebe''.